miRKO Knockout Pipeline Database

Welcome to the Keck Knock-Out Mouse pipeline page. This set of pages was developed by our team to internally track project workflow, and we have made it live in hopes that you will find some helpful data. Jackson Labs will create more formalized pages, and hopefully soon we will add a link to their pages.

Please click on the name of a microRNA below to see our progress towards generating a conditional knock-out mouse for that microRNA. Clicking on the images will reveal some of the underlying data. Also, click on the "microRNA" or "Status" column headings to sort the table by the values in those fields.

microRNA Vector Map family 5'-arm 3'-arm chimeras lacZ Statussort icon
mir-133a-1 mir-133 Construct Created and QCd
mir-133a-2 mir-133 Construct Created and QCd
mir-181b-1 mir-181 Construct Created and QCd
mir-181b-2 mir-181 Construct Created and QCd
mir-181c mir-181 Construct Created and QCd
mir-182 mir-182 Construct Created and QCd
mir-195 mir-15 Construct Created and QCd
mir-199a-2 mir-199 Construct Created and QCd
mir-200a mir-200 Construct Created and QCd
mir-221 mir-221 Construct Created and QCd
mir-295 mir-290 Construct Created and QCd
mir-296 mir-296 Construct Created and QCd
mir-374 mir-374 Construct Created and QCd
mir-451 mir-451 Construct Created and QCd
mir-452 mir-452 Construct Created and QCd
Let-7e let-7 Construct Created and QCd
miR-182/ mir-96/ mir-183
mir-96
mir-182
mir-183
ES Cells have been Targeted
let-7a-2 let-7 ES Cells have been Targeted
miR-100 mir-99 ES Cells have been Targeted
miR-126 mir-126 ES Cells have been Targeted