miRKO Knockout Pipeline Database

Welcome to the Keck Knock-Out Mouse pipeline page. This set of pages was developed by our team to internally track project workflow, and we have made it live in hopes that you will find some helpful data. Jackson Labs will create more formalized pages, and hopefully soon we will add a link to their pages.

Please click on the name of a microRNA below to see our progress towards generating a conditional knock-out mouse for that microRNA. Clicking on the images will reveal some of the underlying data. Also, click on the "microRNA" or "Status" column headings to sort the table by the values in those fields.

microRNAsort icon Vector Map family 5'-arm 3'-arm chimeras lacZ Status
miR-122a mir-122 Construct Created and QCd
miR-124-1 mir-124 Construct Created and QCd
miR-124-2 mir-124 Chimeras have been Produced
miR-124-3 mir-124 Chimeras have been Produced
miR-125b-1 mir-125 Construct Created and QCd
miR-125b-2 mir-125 Chimeras have been Produced
miR-126 mir-126 ES Cells have been Targeted
miR-128-1 mir-128 Construct Created and QCd
mir-128-1 mir-128 Work Begun on Construct
mir-128-2 mir-128 No Data
miR-129-1 mir-129 Transgene was Transmitted through Germli
miR-129-2 mir-129 Construct Created and QCd
miR-130a mir-130
miR-130a
Completed
mir-130b mir-130 ES Cells have been Targeted
miR-130b/ miR-301b mir-130
miR-130b/ miR-301b
Completed
mir-133a-1 mir-133 Construct Created and QCd
miR-133a-1/ miR-1-2
mir-1
mir-133
No Data
mir-133a-2 mir-133 Construct Created and QCd
miR-135a-1 mir-135
Transgene was Transmitted through Germli
miR-135a-2 mir-135 Construct Created and QCd