miRKO Knockout Pipeline Database

Welcome to the Keck Knock-Out Mouse pipeline page. This set of pages was developed by our team to internally track project workflow, and we have made it live in hopes that you will find some helpful data. Jackson Labs will create more formalized pages, and hopefully soon we will add a link to their pages.

Please click on the name of a microRNA below to see our progress towards generating a conditional knock-out mouse for that microRNA. Clicking on the images will reveal some of the underlying data. Also, click on the "microRNA" or "Status" column headings to sort the table by the values in those fields.

microRNAsort icon Vector Map family 5'-arm 3'-arm chimeras lacZ Status
miR-135b mir-135
miR-135b
Completed
miR-137/ cand648 mir-137 Chimeras have been Produced
miR-138-1 mir-138 Completed
miR-138-2 mir-138 Transgene was Transmitted through Germli
miR-139 mir-139 Construct Created and QCd
miR-140 mir-140 No Data
miR-141/ miR-200c mir-200
miR-141/ miR-200c
Completed
miR-142 mir-142 Work Begun on Construct
mir-143 mir-143 ES Cells have been Targeted
miR-144/ miR-451
mir-144
mir-451
Chimeras have been Produced
mir-145 mir-145 ES Cells have been Targeted
miR-145/ mir-143
mir-143
mir-145
Construct Created and QCd
miR-146a mir-146 miR-146a Transgene was Transmitted through Germli
miR-146b mir-146 Work Begun on Construct
mir-146b mir-146 Work Begun on Construct
miR-148a mir-148 Construct Created and QCd
miR-148b mir-148 Construct Created and QCd
miR-149 mir-149 Construct Created and QCd
miR-150 mir-150 Completed
miR-151 mir-28 Construct Created and QCd