miRKO Knockout Pipeline Database

Welcome to the Keck Knock-Out Mouse pipeline page. This set of pages was developed by our team to internally track project workflow, and we have made it live in hopes that you will find some helpful data. Jackson Labs will create more formalized pages, and hopefully soon we will add a link to their pages.

Please click on the name of a microRNA below to see our progress towards generating a conditional knock-out mouse for that microRNA. Clicking on the images will reveal some of the underlying data. Also, click on the "microRNA" or "Status" column headings to sort the table by the values in those fields.

microRNAsort icon Vector Map family 5'-arm 3'-arm chimeras lacZ Status
miR-219-2 mir-219 Completed
mir-221 mir-221 Construct Created and QCd
miR-221/ miR-222 mir-221 Construct Created and QCd
miR-223 mir-223 Work Begun on Construct
mir-23a mir-23 Work Begun on Construct
miR-23a/ miR-27a/ miR-24-2
mir-23
mir-24
mir-27
Construct Created and QCd
mir-23b mir-23 Construct Created and QCd
miR-23b/ miR-24-1/ miR-27b
mir-23
mir-24
mir-27
Chimeras have been Produced
mir-24-1 mir-24 Construct Created and QCd
mir-24-2 mir-24 Construct Created and QCd
miR-25/ mir-93/ mir-106b
mir-17
mir-25
No Data
miR-26a-1 mir-26 Construct Created and QCd
miR-26b mir-26 Construct Created and QCd
mir-27a mir-27 Construct Created and QCd
mir-27b mir-27 Construct Created and QCd
miR-28 mir-28 No Data
mir-290 mir-290 Work Begun on Construct
mir-292 mir-290 Work Begun on Construct
mir-295 mir-290 Construct Created and QCd
mir-296 mir-296 Construct Created and QCd