miRKO Knockout Pipeline Database

Welcome to the Keck Knock-Out Mouse pipeline page. This set of pages was developed by our team to internally track project workflow, and we have made it live in hopes that you will find some helpful data. Jackson Labs will create more formalized pages, and hopefully soon we will add a link to their pages.

Please click on the name of a microRNA below to see our progress towards generating a conditional knock-out mouse for that microRNA. Clicking on the images will reveal some of the underlying data. Also, click on the "microRNA" or "Status" column headings to sort the table by the values in those fields.

microRNAsort icon Vector Map family 5'-arm 3'-arm chimeras lacZ Status
miR-186 mir-186 No Data
miR-185 mir-185 Completed
miR-184 mir-184 Construct Created and QCd
miR-182/ mir-96/ mir-183
mir-96
mir-182
mir-183
ES Cells have been Targeted
mir-182 mir-182 Construct Created and QCd
miR-181d/ miR-181c mir-181 Construct Created and QCd
mir-181c mir-181 Construct Created and QCd
mir-181b-2 mir-181 Construct Created and QCd
mir-181b-1 mir-181 Construct Created and QCd
miR-181a-2/ miR-181b-2 mir-181 Construct Created and QCd
miR-181a-1/ miR-181b-1 mir-181 Construct Created and QCd
miR-17/ miR-18a/ miR-19b-1/ miR-20a/ miR-92a-1
mir-17
mir-19
mir-92
Construct Created and QCd
miR-16-1/ mir-15a mir-15 Chimeras have been Produced
miR-15b/ miR-16-2 mir-15 Chimeras have been Produced
mir-15b mir-15 ES Cells have been Targeted
miR-15a mir-15 No Data
mir-15a mir-15 No Data
miR-155 mir-155 ES Cells have been Targeted
miR-153 mir-153 Construct Created and QCd
miR-152 mir-148 Construct Created and QCd