miRKO Knockout Pipeline Database

Welcome to the Keck Knock-Out Mouse pipeline page. This set of pages was developed by our team to internally track project workflow, and we have made it live in hopes that you will find some helpful data. Jackson Labs will create more formalized pages, and hopefully soon we will add a link to their pages.

Please click on the name of a microRNA below to see our progress towards generating a conditional knock-out mouse for that microRNA. Clicking on the images will reveal some of the underlying data. Also, click on the "microRNA" or "Status" column headings to sort the table by the values in those fields.

microRNAsort icon Vector Map family 5'-arm 3'-arm chimeras lacZ Status
miR-33 mir-33 Construct Created and QCd
mir-33 mir-33 Work Begun on Construct
miR-331 mir-331 Construct Created and QCd
miR-338 mir-338 Construct Created and QCd
miR-339 mir-339
miR-339
Completed
miR-340 mir-340 Construct Created and QCd
miR-342 mir-342 No Data
miR-345 mir-345 No Data
miR-34a mir-34
Chimeras have been Produced
miR-34c/ mir-34b mir-34 Construct Created and QCd
miR-350 mir-350 Construct Created and QCd
miR-361 mir-361 No Data
miR-363/ miR-92a-2/ miR-19b-2/ miR-20b/ miR-18b/ miR-106a
mir-19
mir-92
Construct Created and QCd
miR-365-1 mir-365 Construct Created and QCd
miR-365-2 mir-365 Construct Created and QCd
miR-370 mir-370 No Data
mir-374 mir-374 Construct Created and QCd
miR-375 mir-375 Construct Created and QCd
miR-376a mir-368 Construct Created and QCd
miR-376c mir-368 Construct Created and QCd